The original and still the best! For a fifth year running, our heads of department have been hard at work to create a series of predicted exams for Summer 2026!

Questions increase in difficulty across both papers, with a mix of matching and definition tasks, structured short answer, data interpretation, calculations and 6-mark extended response questions .

All questions are completely original and have been designed from scratch. There has been no reuse of previous exam questions.

This is for the following papers: 8464/B/1H and 8464/B/2H

For Biology Paper 1H:

The paper covers the following specification areas:

4.1 Cell Biology - cell structure, microscopy and magnification, mitosis, differentiation, active transport
• 4.2 Organisation - digestive enzymes, coronary heart disease, lifestyle risk factors, cancer, plant tissues
• 4.3 Infection and Response - human defence systems, antibiotics and resistance, drug development and clinical trials
• 4.4 Bioenergetics - anaerobic respiration and fermentation, aerobic vs anaerobic energy transfer, uses of glucose, the role of nitrate ions

Includes: Question paper and full mark scheme with level descriptors and exemplar responses for all 6-mark questions.

For Biology Paper 2H:

The paper covers the following specification areas:

• 4.5 Homeostasis and Response - the nervous system and reflex arcs, reaction time investigations, comparing nervous and endocrine coordination, hormones in human reproduction, the menstrual cycle, IVF and evaluating fertility treatment
• 4.6 Inheritance, Variation and Evolution - genetic terminology, Punnett squares and probability, inherited disorders, mutation and enzyme function, gene therapy and the role of vectors, natural selection and antibiotic resistance, classification
• 4.7 Ecology - sampling techniques, food chains and interdependence, factors affecting distribution of species, deforestation, global warming, the carbon cycle and biodiversity conservation

Includes: Question paper and full mark scheme with level descriptors and exemplar responses for all 6-mark questions.

Disclaimer: This document was created by department heads with many years of experience teaching the AQA Combined Science: Trilogy course. We cannot however guarantee that it is an accurate representation of the 2026 examinations and students should not treat it as such. Please use this as an aid, alongside other methods of revision.